Unit of Gastroenterology and Digestive Endoscopy, AUSL Bologna Bellaria-Maggiore Hospital, Bologna, Italy.
Dig Liver Dis. 2011 Aug;43(8):647-52. doi: 10.1016/j.dld.2011.04.005. Epub 2011 May 17.
The difference in the diagnostic accuracy of 22- versus 25-gauge needles in EUS-FNA is not clear.
To compare the rates of technical success, diagnostic accuracy and complications of EUS-FNA performed with 22-gauge and 25-gauge needles on the same solid pancreatic mass.
All patients with solid pancreatic masses evaluated from September 2007 to December 2008 were enrolled and underwent EUS-FNA with both 22- and 25-gauge needles with randomisation of needle sequence. The accuracy of the EUS-FNA was determined by comparing the cytological results with the final surgical pathological diagnoses or with the results of a clinical follow-up. A cytological score with different qualitative parameters was created, and a comparison between these parameters was carried out for each needle.
Fifty patients with 50 pancreatic masses were recruited. Technical success was 100% and no complications occurred. Diagnostic accuracy was 94% and 86% for the 25- and 22-gauge needles, respectively. Analysis of the cytological score showed a tendency towards the 25-gauge needle, although the difference was not statistically significant.
EUS-FNA performed with 22- or 25-gauge needles had the same diagnostic accuracy. Our study results confirm a significant trend towards a better cytological diagnosis for the 25-gauge needle.
EUS-FNA 中 22 号和 25 号针的诊断准确性差异尚不清楚。
比较在同一胰腺实性肿块上使用 22 号和 25 号针进行 EUS-FNA 的技术成功率、诊断准确性和并发症发生率。
所有 2007 年 9 月至 2008 年 12 月评估的胰腺实性肿块患者均入组，并使用 22 号和 25 号针进行随机序贯 EUS-FNA。EUS-FNA 的准确性通过将细胞学结果与最终的手术病理诊断或临床随访结果进行比较来确定。创建了具有不同定性参数的细胞学评分，并对每种针进行了这些参数之间的比较。
共纳入 50 例胰腺肿块患者。技术成功率为 100%，无并发症发生。25 号和 22 号针的诊断准确率分别为 94%和 86%。对细胞学评分的分析显示，25 号针有更好的趋势，但差异无统计学意义。
使用 22 号或 25 号针进行 EUS-FNA 具有相同的诊断准确性。我们的研究结果证实，25 号针在细胞学诊断方面具有显著优势。
