Rita Enrico, Marinelli Alessandro, Scipione Pietro, Cecchetti Paolo, Molini Silvano, Misiani Agostino, Pupita Giuseppe, Capucci Alessandro
Clinica di Cardiologia, Azienda Ospedaliera Ospedali Riuniti di Ancona, Universita Politecnica delle Marche.
G Ital Cardiol (Rome). 2011 May;12(5):383-7. doi: 10.1714/643.7505.
Left ventricular dysfunction due to frequent isolated premature ventricular complexes originating from the right ventricular outflow tract (RVOT) in patients without structural heart disease and in the absence of sustained ventricular tachycardia is a rare and poorly characterized entity. Successful identification and radiofrequency catheter ablation of the focal source of ventricular ectopy is the most effective treatment for these patients, leading to a complete normalization of ventricular dimensions and contractile function. In this article, we report two cases of left ventricular dysfunction resulting from frequent isolated premature ventricular complexes originating from the RVOT. After successful ablation of the ectopic focus, improvement of functional status and left ventricular function was observed in both patients, confirming the initial diagnostic hypothesis of a cardiomyopathy induced by repetitive ventricular ectopic beats from the RVOT.
在无结构性心脏病且无持续性室性心动过速的患者中，由起源于右心室流出道（RVOT）的频发孤立室性早搏导致的左心室功能障碍是一种罕见且特征描述不清的病症。成功识别并对室性异位搏动的局灶性来源进行射频导管消融是这些患者最有效的治疗方法，可使心室大小和收缩功能完全恢复正常。在本文中，我们报告了两例由起源于RVOT的频发孤立室性早搏导致左心室功能障碍的病例。在成功消融异位灶后，两名患者的功能状态和左心室功能均有改善，证实了最初关于RVOT重复性室性异位搏动诱发心肌病的诊断假设。
