Liver Transplant Unit Victoria, Austin Health, Victoria, Australia.
J Gastroenterol Hepatol. 2011 Aug;26(8):1221-8. doi: 10.1111/j.1440-1746.2011.06783.x.
Three decades after the first intestinal transplant was performed in humans, this life-saving procedure has come of age and now offers hope of long-term survival in a small group of patients with life-threatening complications of intestinal failure and parenteral nutrition. Success rates have greatly improved, largely through advances in immunosuppression protocols, improved surgical technique and postoperative care, and accumulated experience. Management of the intestinal transplant recipient entails careful surveillance, prevention, and treatment of rejection and infection, as well as optimization of feeding and nutrition. With this approach, survival and quality of life are demonstrably improved, such that intestinal transplantation is now an established and accepted procedure for this very select group of highly-complex patients.
在首例人类肠道移植手术完成三十年后，这项拯救生命的手术已经成熟，为患有危及生命的肠道衰竭和肠外营养并发症的一小部分患者提供了长期生存的希望。成功率有了很大提高，这主要得益于免疫抑制方案的进步、手术技术和术后护理的改进以及经验的积累。肠道移植受者的管理需要仔细监测、预防和治疗排斥和感染，以及优化喂养和营养。通过这种方法，生存和生活质量得到了明显改善，因此，肠道移植现在已经成为这一非常复杂的高度选择患者群体的既定和公认的手术。
