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老年癫痫:未来的研究和临床方向。

Geriatric epilepsy: research and clinical directions for the future.

机构信息

Department of Neurology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

出版信息

Epilepsy Behav. 2011 Sep;22(1):103-11. doi: 10.1016/j.yebeh.2011.04.005. Epub 2011 May 19.

Abstract

There is a growing awareness of the need for improved treatment and care of older adults with epilepsy. The present review article highlights key clinical and research issues in the emerging field of geriatric epilepsy. Drs. Martin and Schmidt explore the scope of the problems in the field, outline topic areas including cognitive health/dementia, and diagnostic challenges, and also present important research questions that should be considered for the future. As part of this presentation, we will highlight the work of two promising young investigators whose work holds great promise for the field of geriatric epilepsy. Dr. Roberson will discuss his work focusing on the relationship of epilepsy and cognitive impairment, particularly as it relates to Alzheimer's disease pathology including tau and its role in epileptiform activity. Dr. Hope will outline key issues, as well as her work, relating to defining and measuring quality care in geriatric epilepsy.

摘要

人们越来越意识到需要改善对老年癫痫患者的治疗和护理。本文重点介绍了老年癫痫这一新兴领域的关键临床和研究问题。Martin 和 Schmidt 博士探讨了该领域存在的问题范围,概述了包括认知健康/痴呆、诊断挑战等主题领域,并提出了未来应考虑的重要研究问题。在本次演讲中,我们将重点介绍两位有前途的年轻研究员的工作,他们的工作为老年癫痫领域带来了巨大的希望。Roberson 博士将讨论他的工作,重点关注癫痫与认知障碍的关系,特别是与阿尔茨海默病病理相关的 tau 及其在癫痫样活动中的作用。Hope 博士将概述与定义和衡量老年癫痫护理质量相关的关键问题及其工作。

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