Advanced Photonics Center, School of Electronic Science and Engineering, Southeast University, Nanjing 210096, People's Republic of China.
Nanotechnology. 2011 Jul 8;22(27):275605. doi: 10.1088/0957-4484/22/27/275605. Epub 2011 May 20.
To prepare biologically available Zn-based NCs in aqueous solution, we herein reported the synthesis of aqueous Cu:ZnSe/ZnS NCs with internally doped aqueous Cu:ZnSe NCs as the core template. Due to the dual protection of Cu impurities by the ZnSe core and ZnS shells, the as-prepared Cu:ZnSe/ZnS NCs show excellent stability in the open air, which overcomes the intrinsic instability of traditional aqueous Cu:ZnSe NCs. The as-prepared Cu:ZnSe/ZnS NCs possess extremely good stability, good biocompatibility and lower cytotoxicity, and thus can be used as a promising candidate for fluorescent NC-based biological applications.
为了在水溶液中制备具有生物利用度的 Zn 基 NCs，我们在此报道了具有内部掺杂的水性 Cu:ZnSe NCs 作为核模板的水性 Cu:ZnSe/ZnS NCs 的合成。由于 Cu 杂质被 ZnSe 核和 ZnS 壳的双重保护，所制备的 Cu:ZnSe/ZnS NCs 在开放空气中表现出优异的稳定性，克服了传统水性 Cu:ZnSe NCs 的固有不稳定性。所制备的 Cu:ZnSe/ZnS NCs 具有极好的稳定性、良好的生物相容性和较低的细胞毒性，因此可以作为一种有前途的荧光 NC 基生物应用候选材料。
