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[症状性血管痉挛。临床表现]

[Symptomatic vasospasm. Clinical manifestations].

作者信息

Scherle-Matamoros C E, Pérez-Nellar J, Fernández-Cue L

机构信息

Unidad de Ictus, Servicio de neurología, Hospital CQ "Hermanos Ameijeiras", Ciudad Habana, Cuba.

出版信息

Neurocirugia (Astur). 2011 Apr;22(2):116-22.

Abstract

INTRODUCTION

Symptomatic vasospasm in the setting of a subarachnoid hemorrhage is a complication of difficult diagnosis in some clinical situations. Objectives. Describe the clinical characteristics of cerebral vasospasm demonstrated by neurovascular studies in patients with ruptured saccular aneurysm.

PATIENTS AND METHODS

19 consecutive patients with symptomatic vasospasm, evaluated with TCD and any variant of neurovascular study with contrast injection. All these cases were in degrees between 1 and 3 of the World Federation of Neurological Surgeons Scale.

RESULTS

The cognitive and behavioral manifestations were the most frequent (53%), followed by neurological focal deficits (26%). Clinical vasospasm occurred most frequently between day 9 and 10. Vasospasm is predominant in the arteries of the anterior circulation. The high mortality (42%) and the antecedent of arterial hypertension characterized the group with symptomatic vasospasm. There was no statistical relationship between the result of the scale of Fisher and the symptomatic vasospasm. All the TCD parameters had statistical significance.

CONCLUSIONS

The clinical manifestations more frequently associated with symptomatic vasospasm were cognitive and behavioral. This group of patients is characterized by a high mortality. The TCD is a test of great value to predict cerebral ischemia due to vasospasm.

摘要

引言

蛛网膜下腔出血情况下的症状性血管痉挛在某些临床情况下是一种诊断困难的并发症。目的:描述囊状动脉瘤破裂患者经神经血管研究证实的脑血管痉挛的临床特征。

患者与方法

连续19例有症状性血管痉挛的患者,接受了经颅多普勒(TCD)检查以及任何一种注射造影剂的神经血管研究变体检查。所有这些病例的世界神经外科医师联合会(WFNS)分级均在1至3级之间。

结果

认知和行为表现最为常见(53%),其次是神经局灶性缺损(26%)。临床血管痉挛最常发生在第9天和第10天之间。血管痉挛在前循环动脉中最为常见。高死亡率(42%)和动脉高血压病史是有症状性血管痉挛患者群体的特征。Fisher分级结果与症状性血管痉挛之间无统计学关系。所有TCD参数均具有统计学意义。

结论

与症状性血管痉挛最常相关的临床表现是认知和行为方面。这组患者的特征是高死亡率。TCD是预测血管痉挛所致脑缺血的一项很有价值的检查。

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