[气候因素与多发性硬化症的临床多态性]

[Climatic factors and clinical polymorphism of multiple sclerosis].

作者信息

Alaev B A, Aslanov A M

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1990;90(2):9-12.

Abstract

A study was made of the clinical manifestations of multiple sclerosis (MS) in 106 Russians born in the European part of the USSR, who moved afterwards to Uzbekistan at different times. Analysis of the two patients' groups demonstrated that in those who fell ill in Uzbekistan, MS started at an older age and ran a more malignant course as compared to those who had fallen ill in the European part of the USSR. Therefore, a model has been tried, permitting one to assess the influence of the climatogeographic conditions of the region under study on the clinical polymorphism of MS after exclusion of the populational differences between the examinees.

摘要

对106名出生于苏联欧洲部分、后来在不同时间移居乌兹别克斯坦的俄罗斯人的多发性硬化症（MS）临床表现进行了研究。对两组患者的分析表明，与那些在苏联欧洲部分患病的人相比，在乌兹别克斯坦患病的人MS发病年龄更大，病程更凶险。因此，尝试建立了一个模型，在排除受检者群体差异后，该模型可用于评估所研究地区的气候地理条件对MS临床多态性的影响。