Higashi-Shingai Kayoko, Imai Takao, Takeda Noriaki, Uno Atsuhiko, Nishiike Suetaka, Horii Arata, Kitahara Tadashi, Fuse Yuka, Hashimoto Misako, Senba Osamu, Suzuki Tsuyoshi, Fujita Toshiaki, Otsuki Hideo, Inohara Hidenori
Depatrment of Otorhinolaryngology--Head and Neck Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suitashi, Osaka, Japan.
Auris Nasus Larynx. 2012 Apr;39(2):216-9. doi: 10.1016/j.anl.2011.03.005. Epub 2011 May 23.
We report the case of a 58-year-old female patient who consulted our Department complaining of positional vertigo and showing spontaneous upbeat nystagmus (UBN) in darkness.
We analyzed her UBN three-dimensionally. The MRI scan revealed the astrocytoma in the left cerebellum involving the cerebellar vermis.
Three-dimensional analysis showed a spontaneous UBN rotating around the intra-aural axis in the pitch plane.
Since the cerebellar vermis is known to plays an inhibitory role on the central vertical vestibule-ocular reflex (VOR), the present results suggest that the spontaneous UBN in darkness observed in this patient was induced by an imbalance of central vertical VOR tone.
我们报告一例58岁女性患者，她因位置性眩晕前来我科就诊，且在黑暗中出现自发性上跳性眼震（UBN）。
我们对她的上跳性眼震进行了三维分析。磁共振成像（MRI）扫描显示左侧小脑星形细胞瘤累及小脑蚓部。
三维分析显示在俯仰平面内围绕耳内轴旋转的自发性上跳性眼震。
由于已知小脑蚓部对中枢垂直前庭眼反射（VOR）起抑制作用，目前的结果表明该患者在黑暗中观察到的自发性上跳性眼震是由中枢垂直VOR张力失衡引起的。
