Lee Seung-Chul, Lee Seok-Ho, Lee Kyu-Yong, Lee Young Joo, Koh Seong-Ho
Department of Neurology, College of Medicine, Hanyang University, 249-1 Guri Hospital, Gyomun-dong, Guri-si, Gyeonggi-do, 471-701, Korea.
J Clin Neurosci. 2009 Apr;16(4):563-5. doi: 10.1016/j.jocn.2008.05.027. Epub 2009 Feb 13.
Upbeat nystagmus is known to be caused by an imbalance of the vertical vestibulo-ocular reflex (VOR), favoring downward VOR activity, due to bilateral lesions of the medulla, ventral tegmentum, anterior cerebellar vermis, adjacent brachium conjunctivum and the midbrain. We report on two patients who had transient upbeat nystagmus due to unilateral pontine infarction that may have disrupted bilateral upward VOR pathways running in the ventral tegmental tracts.
上跳性眼球震颤已知是由垂直前庭眼反射（VOR）失衡引起的，由于延髓、腹侧被盖区、小脑前蚓部、相邻结合臂和中脑的双侧病变，导致向下的VOR活动占优势。我们报告了两名因单侧脑桥梗死而出现短暂性上跳性眼球震颤的患者，单侧脑桥梗死可能破坏了腹侧被盖束中运行的双侧向上VOR通路。
