Yoshioka H, Nakagawa K, Shindou H, Ono Y, Kawakami A, Mabuchi N, Arita S, Fujii K, Hamada T, Ishida O
Department of Radiology, Kinki University School of Medicine, Osaka, Japan.
Acta Radiol. 1990 Jan;31(1):63-7.
Transcatheter chemo-embolization (TCE) in hepatocellular carcinoma (HCC) was performed in 38 patients. The patients were examined by MR imaging before TCE as well as one week and 4 to 5 weeks after TCE. The tumor signal intensity in T2 weighted images increased in 13 cases and decreased in 19 cases after TCE. Increased intensity seemed to reflect intra-tumoral hemorrhage or liquefaction accompanying tumor necrosis. Decreased intensity seemed to reflect coagulation necrosis. In 9 of 18 cases followed over a 2-month period the signal intensity had decreased in both T1 and T2 weighted images. In these patients the tumor showed no recurrence at angiography and the decreased signal seemed to reflect the completion of coagulation necrosis. A hyper- and/or hypointense rim around the tumor appeared in 22 cases. These changes were thought to be perifocal edema or granulation tissue around the tumor. MR imaging was useful in evaluating the necrotic process of the tumor after TCE.
对38例肝细胞癌患者实施了经导管化疗栓塞术（TCE）。在TCE术前以及术后1周和4至5周对患者进行了磁共振成像检查。TCE术后，13例患者T2加权图像上的肿瘤信号强度增加，19例患者的肿瘤信号强度降低。信号强度增加似乎反映了伴随肿瘤坏死的瘤内出血或液化。信号强度降低似乎反映了凝固性坏死。在随访2个月的18例患者中，有9例患者的T1加权和T2加权图像上的信号强度均降低。在这些患者中，血管造影显示肿瘤无复发，信号强度降低似乎反映了凝固性坏死的完成。22例患者的肿瘤周围出现了高信号和/或低信号环。这些变化被认为是肿瘤周围的灶周水肿或肉芽组织。磁共振成像有助于评估TCE术后肿瘤的坏死过程。
