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[胰岛素依赖型糖尿病患者外周神经病变与自主神经病变之间的关系]

[The relation between peripheral and autonomic neuropathies in insulin-dependent diabetics].

作者信息

Boucek P, Vondrová H, Bartos V, Malý J, Hýza Z

机构信息

Program výzkumu kardiovaskulárních nemocí, Institutu klinické a experimentální medicíny, Praha.

出版信息

Cas Lek Cesk. 1990 Apr 20;129(16):494-7.

PMID:2160329
Abstract

Eighty-eight type I diabetics were subjected to neurological and myographic examination and tests were performed assessing the condition of the vegetative nervous system. Forty-four patients (50% of the group) suffered from diabetic nephropathy with different expression in the stage of chronic renal failure. The authors revealed significant positive correlation between the results of tests of vegetative neuropathy and all evaluated parameters of the neurological and electromyographic finding. In patients with a S-creatinine level above 125 mumol/l in both tests of vegetative neuropathy and in all examined parameters of peripheral nerves highly significantly lower values were recorded than in diabetic patients with normal renal function. In diabetics without renal insufficiency, however, the correlations between the findings on the autonomous and peripheral nervous system were also statistically significant.

摘要

88名I型糖尿病患者接受了神经学和肌电图检查,并进行了评估自主神经系统状况的测试。44名患者(占该组的50%)患有糖尿病肾病,在慢性肾衰竭阶段有不同表现。作者发现自主神经病变测试结果与神经学和肌电图检查所有评估参数之间存在显著正相关。在血清肌酐水平高于125μmol/l的患者中,自主神经病变测试以及所有外周神经检查参数所记录的值均显著低于肾功能正常的糖尿病患者。然而,在无肾功能不全的糖尿病患者中,自主神经系统和外周神经系统检查结果之间的相关性也具有统计学意义。

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