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Ochsner J. 2011 Spring;11(1):78-80.
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本文引用的文献

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The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.剖宫产术后腹横肌平面阻滞的镇痛效果:一项随机对照试验。
Anesth Analg. 2008 Jan;106(1):186-91, table of contents. doi: 10.1213/01.ane.0000290294.64090.f3.
2
Pregnancy and primary pulmonary hypertension : successful outcome with epoprostenol therapy.妊娠与原发性肺动脉高压:依前列醇治疗取得成功结果
Chest. 2001 Mar;119(3):973-5. doi: 10.1378/chest.119.3.973.
3
A survey of diagnostic practices and the use of epoprostenol in patients with primary pulmonary hypertension.一项关于原发性肺动脉高压患者诊断方法及依前列醇使用情况的调查。
Chest. 1998 Nov;114(5):1269-75. doi: 10.1378/chest.114.5.1269.
4
Eisenmenger's syndrome in pregnancy: maternal and fetal mortality in the 1990s.
Br J Obstet Gynaecol. 1998 Aug;105(8):921-2. doi: 10.1111/j.1471-0528.1998.tb10240.x.
5
Outcome of pulmonary vascular disease in pregnancy: a systematic overview from 1978 through 1996.妊娠期肺血管疾病的结局:1978年至1996年的系统综述
J Am Coll Cardiol. 1998 Jun;31(7):1650-7. doi: 10.1016/s0735-1097(98)00162-4.
6
Arginine vasopressin induces endothelium-dependent vasodilatation of the pulmonary artery. V1-receptor-mediated production of nitric oxide.精氨酸加压素可诱导肺动脉的内皮依赖性血管舒张。V1受体介导一氧化氮的产生。
Chest. 1993 Apr;103(4):1241-5. doi: 10.1378/chest.103.4.1241.
7
Long-term treatment of primary pulmonary hypertension with continuous intravenous epoprostenol (prostacyclin).持续静脉输注依前列醇(前列环素)对原发性肺动脉高压的长期治疗
Lancet. 1984 May 12;1(8385):1046-7. doi: 10.1016/s0140-6736(84)91452-1.

严重肺动脉高压合并右向左分流患者剖宫产的硬膜外麻醉

Epidural Anesthesia for Cesarean Delivery in a Patient With Severe Pulmonary Artery Hypertension and a Right-to-Left Shunt.

作者信息

Krenz Elizabeth I, Hart Stuart R, Russo Melissa, Alkadri Mohi

出版信息

Ochsner J. 2011 Spring;11(1):78-80.

PMID:21603339
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3096160/
Abstract

A 38-year-old woman with severe pulmonary artery hypertension and a right-to-left shunt of unknown etiology presented at 32 weeks' gestational age. Determination of the cause of her pulmonary hypertension by transesophageal echocardiography was delayed until after delivery secondary to anesthetic risk. She was successfully anesthetized for cesarean delivery using epidural anesthesia. Systemic vascular resistance was maintained using phenylephrine hydrochloride before delivery and vasopressin after delivery. Transesophageal echocardiography after delivery revealed a patent foramen ovale, indicating a diagnosis of idiopathic pulmonary artery hypertension and a very poor prognosis. Differentiating between Eisenmenger syndrome and idiopathic pulmonary artery hypertension may not be important for determining the optimal anesthetic management of patients with pulmonary hypertension but is important in assessing long-term prognosis.

摘要

一名38岁患有严重肺动脉高压且病因不明的右向左分流的女性,在孕32周时就诊。由于麻醉风险,经食管超声心动图确定其肺动脉高压病因的检查推迟至分娩后。她通过硬膜外麻醉成功接受剖宫产手术麻醉。分娩前使用盐酸去氧肾上腺素维持体循环阻力,分娩后使用血管加压素。分娩后经食管超声心动图显示卵圆孔未闭,提示特发性肺动脉高压诊断且预后极差。区分艾森曼格综合征和特发性肺动脉高压对于确定肺动脉高压患者的最佳麻醉管理可能并不重要,但对于评估长期预后很重要。