Grise Mark A, Verma Anil
Department of Cardiology, Ochsner Clinic Foundation, New Orleans, LA.
Ochsner J. 2009 Winter;9(4):220-6.
It is estimated that as many as 1,000,000 people in the United States have chronic symptomatic coronary artery disease (often referred to as refractory angina) that is recalcitrant to medical therapy and unamenable to conventional revascularization procedures. Patients have reproducible lifestyle-limiting symptoms of chest pain, shortness of breath, and easy fatigability. Several new therapies are available to treat this difficult patient population, including newer drugs, enhanced external counterpulsation, transmyocardial revascularization, and cell-based therapies. This article reviews the current state of the art for treatment of refractory angina.
据估计,美国多达100万人患有慢性症状性冠状动脉疾病(常被称为顽固性心绞痛),这种疾病对药物治疗无效且无法进行传统的血运重建手术。患者有可重现的限制生活方式的胸痛、呼吸急促和易疲劳症状。有几种新的疗法可用于治疗这一难治性患者群体,包括新型药物、增强型体外反搏、经心肌血运重建和基于细胞的疗法。本文综述了顽固性心绞痛治疗的当前技术水平。