Fogagnolo Leticia, Cintra Maria Letícia, Velho Paulo Eduardo Neves Ferreira
Dermatology Department, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
An Bras Dermatol. 2011 Mar-Apr;86(2):333-5. doi: 10.1590/s0365-05962011000200017.
Angiokeratomas are benign tumors characterized by ectasia of blood vessels in the papillary dermis associated with acanthosis and hyperkeratosis of the epidermis. Dermatological examination of angiokeratomas of Fordyce is characterized by papular keratotic lesions of erythematous-violet color. They are more common in the scrotum, and vulvar involvement is rarely reported. Histopathology is particularly important to distinguish them from other benign and malignant tumors. The article reports the case of a middle-aged black woman with a history of chronic constipation, varicose veins of the lower limbs and cesarean section performed 20 years ago who had had multiple vulvar angiokeratomas for three months.
血管角皮瘤是一种良性肿瘤，其特征为乳头层真皮内血管扩张，并伴有表皮棘层增厚和角化过度。福代斯血管角皮瘤的皮肤检查表现为紫红色丘疹性角化病变。它们在阴囊更为常见，外阴受累的报道很少。组织病理学对于将它们与其他良性和恶性肿瘤区分开来尤为重要。本文报道了一例中年黑人女性病例，该患者有慢性便秘、下肢静脉曲张病史，20年前行剖宫产，三个月来患有多发性外阴血管角皮瘤。
