Rosa Dário Júnior de Freitas, Matias Fernanda de Abreu Toledo, Cedrim Sâmya Diégues, Machado Ronaldo Figueiredo, Sá Alessandra Almeida Montenegro de, Silva Vânia Carolina Piccinini
Dermatology Research Unit, Teaching Hospital of the Federal University of Juiz de Fora (UFJF), Juiz de Fora, Minas Gerais, Brazil.
An Bras Dermatol. 2011 Mar-Apr;86(2):336-8. doi: 10.1590/s0365-05962011000200018.
Multiple sclerosis is an inflammatory demyelinating disease of presumed autoimmune origin that affects the central nervous system. The main form of therapy is based on the use of immunomodulators such as interferon beta, which are usually well tolerated. Skin manifestations resulting from treatment with interferon beta-1b consist principally of reactions at the site of subcutaneous application of the drug. The present case report describes a female patient who developed an acneiform eruption resulting from treatment with interferon beta-1b.
多发性硬化症是一种推测为自身免疫性起源的炎症性脱髓鞘疾病，会影响中枢神经系统。主要的治疗方式是使用免疫调节剂，如β-干扰素，这类药物通常耐受性良好。使用β-1b干扰素治疗所导致的皮肤表现主要是药物皮下注射部位的反应。本病例报告描述了一名女性患者，她因使用β-1b干扰素治疗而出现了痤疮样皮疹。
