重组干扰素β注射导致多发性硬化症患者出现皮肤溃疡和脓疱型银屑病发作。
Cutaneous ulcerations and pustular psoriasis flare caused by recombinant interferon beta injections in patients with multiple sclerosis.
作者信息
Webster G F, Knobler R L, Lublin F D, Kramer E M, Hochman L R
机构信息
Department of Dermatology, Jefferson Medical College, Philadelphia, USA.
出版信息
J Am Acad Dermatol. 1996 Feb;34(2 Pt 2):365-7. doi: 10.1016/s0190-9622(07)80010-7.
PMID:8655728
Abstract
Seven patients with multiple sclerosis who were receiving subcutaneous injections of recombinant interferon beta had pain followed by ulceration at the injection site. An eighth patient had a pustular flare of her usually mild psoriasis. No evidence of infection or contaminated medication was found.
摘要
7名正在接受重组干扰素β皮下注射的多发性硬化症患者在注射部位出现疼痛，随后出现溃疡。第8名患者原本轻微的银屑病出现脓疱性皮疹。未发现感染或药物污染的证据。
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