口服N-乙酰半胱氨酸治疗透析引起的假性卟啉症。

Pseudoporphyria induced by dialysis treated with oral N-acetylcysteine.

作者信息

Guiotoku Marcelo Massaki, Pereira Fabíola de Paula, Miot Hélio Amante, Marques Mariângela Esther Alencar

机构信息

Departamento de Dermatologia e Radioterapia, Faculdade de Medicina, Universidade Paulista Julio de Mesquita Filho, Botucatu, SP, Brasil.

出版信息

An Bras Dermatol. 2011 Mar-Apr;86(2):383-5. doi: 10.1590/s0365-05962011000200031.

DOI:10.1590/s0365-05962011000200031

PMID:21603831

Abstract

Pseudoporphyria is a rare bullous dermatosis that clinically and histopathologically is similar to porphyria cutanea tarda. It mainly affects patients with chronic renal failure on peritoneal dialysis or hemodialysis. Medications can also be involved in the etiology. Diagnosis and management of this condition is a challenge for dermatologists. The authors report a case of pseudoporphyria related to dialysis with favorable outcome after the use of oral N-acetylcysteine.

摘要

假性卟啉病是一种罕见的大疱性皮肤病，在临床和组织病理学上与迟发性皮肤卟啉病相似。它主要影响接受腹膜透析或血液透析的慢性肾衰竭患者。药物也可能参与其病因。对皮肤科医生来说，这种疾病的诊断和管理是一项挑战。作者报告了一例与透析相关的假性卟啉病病例，在使用口服N-乙酰半胱氨酸后取得了良好的效果。