Department of Dermatology, Our Lady of Lourdes Hospital, Drogheda, Dublin, Ireland.
Australas J Dermatol. 2011 May;52(2):e1-3. doi: 10.1111/j.1440-0960.2010.00625.x. Epub 2010 Feb 26.
A newborn baby boy was referred to the Paediatric Dermatology Unit with a solitary asymptomatic nodule overlying his right nasolabial fold. Complete physical examination, full blood count, serum chemistry, liver function tests and baseline imaging were unremarkable. Histopathological examination showed an atypical dermal infiltrate of mononuclear cells that stained positive with CD1a and S100. A diagnosis of congenital solitary Langerhans cell histiocytoma was made. The lesion completely resolved by 4 months of age. The baby is now 15 months old and repeat systemic evaluation has remained normal.
一个新生男婴因右侧鼻唇沟上方有一个单发无症状结节而被转至儿科皮肤科。全面的体格检查、全血细胞计数、血清化学、肝功能检查和基线影像学检查均无异常。组织病理学检查显示单核细胞的非典型真皮浸润，CD1a 和 S100 染色阳性。诊断为先天性孤立性朗格汉斯细胞组织细胞增生症。病变在 4 个月大时完全消退。婴儿现在 15 个月大，重复全身评估仍正常。
