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播散性皮肤型鼻孢子菌病:氨苯砜治疗后的光镜改变。

Disseminated cutaneous with nasopharyngeal rhinosporidiosis: Light microscopy changes following dapsone therapy.

机构信息

Department of Dermatology, Seth GS Medical College and KEM Hospital, Parel, Mumbai, India.

出版信息

Australas J Dermatol. 2011 May;52(2):e4-6. doi: 10.1111/j.1440-0960.2010.00633.x. Epub 2010 Mar 31.

DOI:10.1111/j.1440-0960.2010.00633.x
PMID:21605088
Abstract

We report a case of disseminated cutaneous and nasopharyngeal rhinosporidiosis in a 48-year-old man. The patient complained of a 6-month history of six subcutaneous skin-coloured swellings on the body and a 5-year history of a pea-sized swelling on the inner aspect of the left lower eyelid. Histopathological examination from one of these lesions showed multiple globular cysts packed with endospores that were typical of rhinosporidiosis. We report this case because of its rarity and to describe the morphological effects of dapsone in promotion of a host inflammatory response to the organism.

摘要

我们报告了一例 48 岁男性患者的播散性皮肤和鼻咽部鼻孢子虫病。该患者诉 6 个月来全身有 6 个皮下肤色肿胀,5 年来左眼内下眼睑有豌豆大小的肿胀。其中一个病变的组织病理学检查显示多个充满内生孢子的球形囊肿,这是鼻孢子虫病的典型特征。我们报告这个病例是因为它的罕见性,并描述了氨苯砜在促进宿主对该生物体的炎症反应方面的形态学作用。

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Disseminated cutaneous with nasopharyngeal rhinosporidiosis: Light microscopy changes following dapsone therapy.播散性皮肤型鼻孢子菌病:氨苯砜治疗后的光镜改变。
Australas J Dermatol. 2011 May;52(2):e4-6. doi: 10.1111/j.1440-0960.2010.00633.x. Epub 2010 Mar 31.
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