Department of Radiology, Indiana University School of Medicine, 702 Barnhill Dr, Rm 1053, Indianapolis, IN 46202-5200, USA.
AJR Am J Roentgenol. 2011 Jun;196(6):W689-92. doi: 10.2214/AJR.10.5479.
Since their discovery by Roentgen in 1895, x-rays have contributed to some of the most important advances in science. X-ray crystallography is an imaging technique that uses x-ray diffraction to evaluate the molecular structure of a crystalline solid. This article discusses the critical role played by x-ray crystallography in the elucidation of the structure of DNA.
The story of DNA includes insights on molecular structure provided by x-rays and also lessons on scientific collaboration and innovation that can be applied to radiology today.
自伦琴 1895 年发现 X 射线以来,X 射线已经为科学的一些最重要的进步做出了贡献。X 射线晶体学是一种成像技术,它利用 X 射线衍射来评估晶体固体的分子结构。本文讨论了 X 射线晶体学在阐明 DNA 结构方面所起的关键作用。
DNA 的故事不仅包括 X 射线提供的关于分子结构的见解,还包括对当今放射学领域适用的科学合作和创新的经验教训。