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[乳腺癌保乳手术。1983 - 1988年豪克兰德医院的经验]

[Breast-preserving surgery in breast cancer. Experiences from Haukeland Hospital 1983-1988].

作者信息

Aas T, Valen B, Varhaug J E, Mella O

机构信息

Onkologisk avd, Haukeland sykehus.

出版信息

Nord Med. 1990;105(4):109-12.

PMID:2160649
Abstract

From 1983-88, 97 breast cancers in 94 women were treated with breast-conserving surgery at Haukeland University Hospital. 71 per cent of the tumours were less than 2 cm in diameter and 94 per cent less than 3 cm. 65 had negative axillary nodal status. 90 patients had ductal carcinoma, three of whom also had extensive intraductal carcinoma. Pathological findings in the resection margins (invasive carcinoma, intraductal carcinoma or atypical epithelial hyperplasia) were reasons for reoperation in 14 patients, eight of them by mastectomy. Thus, after completion of initial treatment the breast was preserved in 89 patients. Postoperative irradiation to the breast was given as a routine. Three elderly patients were excepted. Two patients developed ipsilateral breast recurrences after six and 24 months respectively. The first was treated by re-resection and the second by mastectomy. Neither of these showed evidence of distant metastases. Distant metastases were discovered in five patients, two of these have since died.

摘要

1983年至1988年期间,霍科兰大学医院对94名女性的97例乳腺癌患者进行了保乳手术治疗。71%的肿瘤直径小于2厘米,94%的肿瘤直径小于3厘米。65例腋窝淋巴结阴性。90例患者为导管癌,其中3例还伴有广泛的导管内癌。切除边缘的病理结果(浸润性癌、导管内癌或非典型上皮增生)是14例患者再次手术的原因,其中8例接受了乳房切除术。因此,在初始治疗完成后,89例患者的乳房得以保留。常规对乳房进行术后放疗,3例老年患者除外。2例患者分别在6个月和24个月后出现同侧乳房复发。第一例通过再次切除治疗,第二例通过乳房切除术治疗。这两例均未显示远处转移的证据。5例患者发现远处转移,其中2例已经死亡。

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