Vestring T, Achatzy R, Wahlers B, Macha H N, Peters P E
Institut für Klinische Radiologie, Universitätsklinik Münster.
Radiologe. 1990 Apr;30(4):178-84.
Sixty patients with a potentially resectable non-oat-cell lung carcinoma were examined by computed tomography and cervical mediastinoscopy. The sensitivity of computed tomography as opposed to mediastinoscopy was 74% versus 58% and the specificity in 85% versus 100%. Considering the limitations of both methods and the varying prevalence of mediastinal lymph-node metastases associated with peripheral and central lesions, three different situations can be distinguished: 1. with peripheral lesions and a normal mediastinal CT, preoperative mediastinoscopy is unnecessary. 2. With an abnormal mediastinal CT, mediastinoscopy is always indicated irrespective of the location of the tumor. 3. With large central lesions, mediastinoscopy is necessary even when the CT is normal. Using these rules, 37 of 60 mediastinoscopies in our patient group could have been avoided without influencing the resection rate (98%).
对60例具有潜在可切除性的非燕麦细胞肺癌患者进行了计算机断层扫描和颈部纵隔镜检查。与纵隔镜检查相比,计算机断层扫描的敏感性为74%,而纵隔镜检查为58%;特异性分别为85%和100%。考虑到两种方法的局限性以及与周围型和中央型病变相关的纵隔淋巴结转移的不同患病率,可区分出三种不同情况:1. 对于周围型病变且纵隔CT正常的患者,术前无需进行纵隔镜检查。2. 纵隔CT异常时,无论肿瘤位置如何,均应进行纵隔镜检查。3. 对于较大的中央型病变,即使CT正常,也有必要进行纵隔镜检查。按照这些规则,我们患者组的60例纵隔镜检查中有37例本可避免,且不影响切除率(98%)。