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表现为自发性阴囊积血的获得性凝血因子 VIII 抑制剂(获得性血友病 A)

Acquired factor VIII inhibitor (acquired hemophilia A) presenting as spontaneous blood-filled scrotum.

作者信息

Verma Rajanshu, Noack Jill, Vemuri Radhakrishna, Loehrke Mark E

机构信息

Michigan State University/Kalamazoo Center for Medical Studies; and West Michigan Cancer Center, Kalamazoo, MI, USA.

出版信息

South Med J. 2011 May;104(5):368-70. doi: 10.1097/SMJ.0b013e3182142d1d.

Abstract

Acquired hemophilia A, also known as acquired factor VIII deficiency, is an exceedingly rare bleeding diathesis that does not require any personal or family history of bleeding or clotting disorder. Because treatment is available, misdiagnosing or completely missing this diagnosis can be life threatening for patients. Clinicians should be aware that acquired forms of hemophilia do exist and are associated with high morbidity and mortality in elderly adults. We present a case of a 74-year-old man who was diagnosed with acquired factor VIII inhibitor during an admission for community-acquired pneumonia.

摘要

获得性血友病A,也称为获得性因子VIII缺乏症,是一种极为罕见的出血性素质,不需要任何个人或家族出血或凝血障碍病史。由于有可用的治疗方法,误诊或完全漏诊这种疾病对患者可能会危及生命。临床医生应意识到确实存在获得性血友病形式,并且在老年人中与高发病率和死亡率相关。我们报告一例74岁男性患者,他在因社区获得性肺炎入院期间被诊断为获得性因子VIII抑制物。

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