Lörcher U, Peters J, Kollath J
Klinikum JWG-Universität, Zentrum der Radiologie, Frankfurt.
Rofo. 1990 May;152(5):569-73. doi: 10.1055/s-2008-1046923.
The authors performed 68 liver embolizations in 51 patients. As selectively as possible, Lipiodol, to block the capillary bed, and a chemotherapeutic agent were injected into the liver tumors. A CT performed 24 hours after treatment showed the distribution of the contrast medium which is also an indicator of the distribution of the chemotherapeutic agents. It was found that the contrast medium had accumulated not only in the liver but also in the lungs. Here, four different degrees of accumulation were found, according to the amount of Lipiodol used. Embolization of the liver thus involves potential hazards for the lungs, such as microembolisms, pneumonia, and toxic effects of the chemotherapeutic agents.
作者对51例患者进行了68次肝脏栓塞术。尽可能选择性地将用于阻塞毛细血管床的碘油和一种化疗药物注入肝肿瘤。治疗后24小时进行的CT显示了造影剂的分布情况，造影剂的分布也是化疗药物分布的一个指标。结果发现造影剂不仅在肝脏中积聚，还在肺中积聚。根据所用碘油的量，在此发现了四种不同程度的积聚。因此，肝脏栓塞术对肺部存在潜在危害，如微栓塞、肺炎和化疗药物的毒性作用。
