Housini I, Dabbs D J
Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Acta Cytol. 1990 May-Jun;34(3):420-4.
The fine needle aspiration (FNA) findings are presented for a case of perineurioma, a benign soft tissue tumor composed of perineurial cells, which are epithelial-like and ensheath the endoneurial connective tissue space of nerve fibers. A subcutaneous FNA performed on a posterior thigh mass of a 14-month-old boy produced a specimen consisting of numerous spindle-shaped tumor cells with bipolar cytoplasmic extensions and occasional pseudosignet-ring cells in a prominent myxoid background. Cytologically, a diagnosis of benign myxoid tumor was made. Histologic examination of the resected tumor revealed the characteristic features that have been described for perineurioma; the diagnosis was confirmed with immunocytochemical and ultrastructural studies. Perneurioma should be included in the differential diagnosis of benign myxoid neoplasms seen in FNA biopsy specimens.
本文呈现了一例神经束膜瘤的细针穿刺抽吸（FNA）结果。神经束膜瘤是一种由神经束膜细胞构成的良性软组织肿瘤，神经束膜细胞呈上皮样，包绕神经纤维的神经内膜结缔组织间隙。对一名14个月大男孩大腿后部肿块进行的皮下FNA检查产生了一个标本，其中包含大量梭形肿瘤细胞，这些细胞具有双极细胞质突起，在显著的黏液样背景中偶尔可见假印戒细胞。在细胞学上，诊断为良性黏液样肿瘤。对切除肿瘤的组织学检查揭示了已描述的神经束膜瘤的特征性表现；免疫细胞化学和超微结构研究证实了该诊断。在FNA活检标本中见到的良性黏液样肿瘤的鉴别诊断应包括神经束膜瘤。
