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连续膈肌肌电图信号分析:肌萎缩侧索硬化症患者的结果。

Analysis of continuous diaphragm electromyographic signal: results from a patient with amyotrophic lateral sclerosis.

机构信息

Division of Neurology, University Health Network, Room 5EC 306-A, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada.

出版信息

Muscle Nerve. 2011 Jun;43(6):801-6. doi: 10.1002/mus.21985.

Abstract

INTRODUCTION

Analysis of continuous diaphragm electromyography (dEMG) has not been well studied. We describe a system of analyzing continuous dEMG using implanted electrodes.

METHODS

dEMG signal was acquired via two pairs of electrodes near the diaphragm motor points. Raw bursts of dEMG signal were compared to externally captured electrocardiogram (ECG) using adaptive filtering in order to remove cardiac contamination. Differential energy levels were used to identify each dEMG burst, and average amplitude and area values from both hemidiaphragms were aggregated and averaged for the duration of the recording.

RESULTS

A 64-year-old patient with amyotrophic lateral sclerosis underwent three serial dEMG studies every 6 months. An average of three tracings were collected per visit, and all had excellent intertest reliability (κ > 0.8). Average dEMG area correlated with forced vital capacity and mean inspiratory pressure (r(2) > 0.9).

CONCLUSIONS

The approach described represents a comprehensive method for capturing and analyzing continuous diaphragm EMG signal.

摘要

简介

连续膈肌肌电图(dEMG)的分析尚未得到很好的研究。我们描述了一种使用植入式电极分析连续 dEMG 的系统。

方法

dEMG 信号通过两对靠近膈肌运动点的电极采集。使用自适应滤波对原始 dEMG 信号的爆发进行比较,以去除心脏污染。使用差分能量水平来识别每个 dEMG 爆发,并且来自两个半膈肌的平均幅度和面积值在记录期间被聚合和平均。

结果

一名患有肌萎缩性侧索硬化症的 64 岁患者每 6 个月进行三次连续的 dEMG 研究。每次就诊平均采集三条轨迹,所有轨迹的测试间可靠性均非常好(κ>0.8)。平均 dEMG 面积与用力肺活量和平均吸气压力相关(r²>0.9)。

结论

所描述的方法代表了一种用于捕获和分析连续膈肌 EMG 信号的综合方法。

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