Department of Biology, Djillali Liabes University, Sidi Bel Abbes, Algeria.
Eur Rev Med Pharmacol Sci. 2011 Apr;15(4):436-45.
Iron deficiency continues to be one of the most prevalent single-nutrient deficiencies in the world. The current study aimed to estimate the prevalence of iron deficiency anemia (IDA) among pregnant women who attend Antenatal Care Centers in Sidi Bel Abbes, Algeria. The effect of anaemia on infant birth weight was also examined.
The study was conducted during the period March-Mai, 2010 and the sample consisted of 207 pregnant women (in the third trimesters) in the age group (17-41) years. The subjects were not taking iron, folate or vitamin B12 supplements at the time of the study. Blood samples were collected from each pregnant woman and a questionnaire was completed at the time of blood collection. A series of determinations was conducted to determine hemoglobin concentration (Hb); packed cell volume (PCV); corpuscular hemoglobin concentration (MCHC), corpuscular volume (MCV). The effect of anemia on the weight of new born babies was examined by calculating the correlation coefficient of birth weight and hematological indexes.
The overall prevalence of anemia was found to be 46.86%. According to the severity anemia was 36.08% mild, 49.48% moderate and 14.43% severe anemia. The mean values (+/- SD) of haematological indexes were as follows: Hb 9.00 +/- 1.57 g/dl; PCV 27 +/- 5.37%; mean corpuscular haemoglobin concentration (MCHC) 33.75 +/- 2.69 g/dl and mean corpuscular volume (MCV) 75.7 +/- 10.4 fl. The results have shown that 46.39% of the subjects had MCV values less than standard value of 75 fl suggesting a microcytic anemia. The mean haemoglobin concentration was 9 +/- 1.57 g/dl while the mean birth weight was 3201.54 +/- 566.71 g. There was a not significant correlation between the Hb level and the birth weight of the infants (r = 0.28, p > 0.05). The prevalence of low birth weight was 9.2%. There was no statistically significant haemoglobin concentration /foetal birth weight difference among the various hemoglobin concentration (Chi square test = 0.34, p > 0.05).
Anemia had no significant obstetric adverse effects in our pregnant population (Fischer test = 0.06, p > 0.05). There was no statistically significant difference in mean birth weight among the various haemoglobin groups suggesting that other parameters may play important roles in influencing the birth weight than the maternal haemoglobin concentration.
缺铁仍然是世界上最普遍的单一营养素缺乏症之一。本研究旨在估计在阿尔及利亚西迪贝勒阿贝斯的产前保健中心就诊的孕妇中缺铁性贫血(IDA)的患病率。还检查了贫血对婴儿出生体重的影响。
该研究于 2010 年 3 月至 5 月进行,样本包括 207 名年龄在 17-41 岁的孕妇(处于第三个三个月)。研究时,这些受试者未服用铁、叶酸或维生素 B12 补充剂。从每位孕妇采集血样,并在采血时填写一份问卷。进行了一系列测定以确定血红蛋白浓度(Hb);红细胞压积(PCV);红细胞血红蛋白浓度(MCHC),红细胞体积(MCV)。通过计算出生体重和血液学指标的相关系数来检查贫血对新生儿体重的影响。
总体贫血患病率为 46.86%。根据严重程度,贫血分为 36.08%轻度、49.48%中度和 14.43%重度贫血。血液学指标的平均值(+/-SD)如下:Hb 9.00 +/- 1.57 g/dl;PCV 27 +/- 5.37%;平均红细胞血红蛋白浓度(MCHC)33.75 +/- 2.69 g/dl 和平均红细胞体积(MCV)75.7 +/- 10.4 fl。结果表明,46.39%的受试者的 MCV 值低于 75 fl 的标准值,提示小细胞性贫血。平均血红蛋白浓度为 9 +/- 1.57 g/dl,平均出生体重为 3201.54 +/- 566.71 g。Hb 水平与婴儿出生体重之间无显著相关性(r = 0.28,p > 0.05)。低出生体重的患病率为 9.2%。在不同的血红蛋白浓度(卡方检验= 0.34,p > 0.05)之间,血红蛋白浓度/胎儿出生体重无统计学差异。
在我们的孕妇人群中,贫血对产科无明显不良影响(Fischer 检验= 0.06,p > 0.05)。在不同的血红蛋白组中,平均出生体重没有统计学差异,这表明除了母体血红蛋白浓度外,其他参数可能在影响出生体重方面发挥重要作用。