前列倍喜胶囊治疗精液不液化症：一项多中心临床研究

[Qianlie Beixi Capsules for unliquefiable semen: a multi-center clinical study].

作者信息

Sun Xiang-zhou, Yang Huai, Gao Yong, Mao Xiang-ming, Liu Gui-hua, Chen Dong, Huang Yong-han, Wang Shu-sheng, Zhu Cheng-bin, Wang Huai-peng, Zhang Bin, Zhou Shao-hu, Deng Chun-hua

机构信息

Department of Urology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2011 Apr 26;91(16):1100-3.

PMID:21609591

Abstract

OBJECTIVE

To investigate the efficacy and possible action mechanism of Qianlie Beixi Capsules in the treatment of unliquefiable semen.

METHODS

A total of 190 patients with unliquefiable semen were treated with Qianlie Beixi Capsules for 1 or 2 courses (3 weeks per a course). The seminal changes were observed and recorded.

RESULTS

Of the 190 patients in the 1-course treatment arm, 99 were cured and 91 failed to respond after the first course. And the effectiveness rate was 52.1%. Of the 122 patients in the 2-course treatment arm, 81 were cured and 41 failed to respond after the second course. And the effectiveness rate was 66.4%. The efficacy of 2-course regimen was obviously better than that of 1-course regiment. In the meantime, sperm density improved in the 2-course treatment arm. Sperm motility improved slightly in the effective subjects of 1-course treatment arm. All the above results had statistically significant differences (P < 0.05).

CONCLUSION

Qianlie Beixi Capsules is both safe and effective for unliquefiable semen and may shorten the time of seminal liquefaction.

摘要

目的

探讨前列倍喜胶囊治疗精液不液化症的疗效及可能的作用机制。

方法

将190例精液不液化症患者采用前列倍喜胶囊治疗1或2个疗程（每个疗程3周）。观察并记录精液变化情况。

结果

1个疗程治疗组的190例患者中，第1疗程后99例治愈，91例无效，有效率为52.1%。2个疗程治疗组的122例患者中，第2疗程后81例治愈，41例无效，有效率为66.4%。2个疗程方案的疗效明显优于1个疗程方案。同时，2个疗程治疗组精子密度提高。1个疗程治疗组有效患者精子活力略有提高。上述所有结果均有统计学差异（P < 0.05）。