颈部前侧和脐部皮下脂肪组织厚度与阻塞性睡眠呼吸暂停患者相关。

Subcutaneous fat tissue thickness of the anterior neck and umbilicus in patients with obstructive sleep apnea.

机构信息

Department of Otolaryngology, Fatih University, Ankara, Turkey.

出版信息

Otolaryngol Head Neck Surg. 2011 Sep;145(3):505-10. doi: 10.1177/0194599811410272. Epub 2011 May 25.

DOI:10.1177/0194599811410272

PMID:21613627

Abstract

OBJECTIVE

To investigate the differences in thickness of subcutaneous fat tissue of the anterior neck and umbilicus of patients with and without obstructive sleep apnea (OSA), the relationship between thickness of subcutaneous fat tissue of the anterior neck and umbilicus and polysomnographic findings, and the influence of body mass index (BMI), anthropometric findings, and gender.

STUDY DESIGN

Cross-sectional study.

SETTING

Tertiary care university hospital.

SUBJECT AND METHODS

Seventy-three patients with OSA and 24 non-OSA patients were evaluated with polysomnography for 1 night. Anthropometric parameters and BMI were also investigated. Subcutaneous fat tissue thickness of anterior neck and umbilicus was assessed using ultrasound. The thickness of subcutaneous fat tissue adjacent to the submandibular gland, isthmus, hyoid, suprasternal notch, and umbilicus was measured with ultrasound. Data analysis was performed using SPSS.

RESULTS

Apnea-hypopnea index (AHI) was significantly and positively correlated with age (P = .016, r (2) = 0.244), BMI (P < .001, r (2) = 0.416), and anthropometric findings (waist circumference P < .001, r (2) = 0.337; hip circumference P = .008, r (2) = 0.269; neck circumference P = .002, r (2) = 0.309). Minimum oxygen saturation was significantly, negatively correlated with age (P = .002, r (2) = -0.310), BMI (P < .001, r (2) = -0.404), and anthropometric findings (waist circumference P = .005, r (2) = -0.281, hip circumference P < .001, r (2) = -0.353, neck circumference P = .010, r (2) = -0.261). There were no significant differences between the OSA and non-OSA groups with respect to age (P = .178), gender (P = .189), or ultrasonographic findings for subcutaneous fat tissue thickness adjacent to the submandibular gland (P = .480), thyroid isthmus (P = .311), suprasternal notch (P = .950), umbilicus (P = .691), or hyoid (P = .159). Neck circumference (P = .039) and BMI (P = .014) were significantly higher in the OSA group.

CONCLUSION

These indicate that anterior neck and umbilical subcutaneous fat tissue thickness may not contribute to the severity of OSA.

摘要

目的

探讨阻塞性睡眠呼吸暂停（OSA）患者与无 OSA 患者颈前和脐周皮下脂肪厚度的差异，颈前和脐周皮下脂肪厚度与多导睡眠图（PSG）结果的关系，以及体质量指数（BMI）、人体测量学指标和性别对其的影响。

研究设计

横断面研究。

地点

三级护理大学医院。

患者和方法

73 例 OSA 患者和 24 例非 OSA 患者接受了一夜 PSG 评估。还对人体测量学参数和 BMI 进行了调查。使用超声评估颈前和脐周皮下脂肪组织厚度。使用超声测量颈前皮下脂肪组织与下颌下腺、峡部、舌骨、胸骨上切迹和脐之间的厚度。使用 SPSS 进行数据分析。

结果

呼吸暂停-低通气指数（AHI）与年龄（P =.016，r (2) = 0.244）、BMI（P <.001，r (2) = 0.416）和人体测量学指标（腰围 P <.001，r (2) = 0.337；臀围 P =.008，r (2) = 0.269；颈围 P =.002，r (2) = 0.309）呈显著正相关。最低氧饱和度与年龄（P =.002，r (2) = -0.310）、BMI（P <.001，r (2) = -0.404）和人体测量学指标（腰围 P =.005，r (2) = -0.281，臀围 P <.001，r (2) = -0.353，颈围 P =.010，r (2) = -0.261）呈显著负相关。OSA 组与非 OSA 组在年龄（P =.178）、性别（P =.189）或下颌下腺旁（P =.480）、甲状腺峡部（P =.311）、胸骨上切迹（P =.950）、脐部（P =.691）或舌骨（P =.159）超声皮下脂肪组织厚度方面无显著差异。颈围（P =.039）和 BMI（P =.014）在 OSA 组中显著更高。