Dermatology & Andrology Department, Mansoura University, Egypt.
Andrologia. 2011 Oct;43(5):307-11. doi: 10.1111/j.1439-0272.2010.01073.x. Epub 2011 May 26.
The aim of this study was to assess vascular disturbances in the testis of infertile males associated with varicocele. In total, 124 consecutive male subjects were divided into the following groups: healthy fertile controls (n = 10), Gp1 (n = 28); infertile males with subclinical varicocele, Gp2 (n = 26); infertile males with grade I left varicocele, Gp3 (n = 28); infertile males with grade II left varicocele and Gp4 (n = 32); infertile males with grade III left varicocele. They were subjected to colour duplex for pampiniform plexus and scrotal scintigraphy. There was significant decrease in arterial blood velocity, testicular arterial diameters and testicular perfusion especially in high grade varicocele compared with healthy controls. The mean vein diameter demonstrated significant negative correlation with arterial diameter, arterial blood velocity, perfusion index, testicular size and significant positive correlation with perfusion index. The mean testicular size demonstrated significant positive correlation with arterial blood velocity, perfusion index and nonsignificant correlation with arterial diameter. It is concluded that there are significant decreases in testicular volume, testicular perfusion, blood velocity and testicular artery diameter in infertile males with varicocele.
本研究旨在评估精索静脉曲张与不育男性睾丸血管紊乱的关系。共纳入 124 例连续男性患者,分为以下几组:健康生育对照组(n=10)、Gp1 组(n=28);精索静脉曲张亚临床组(n=26);左侧精索静脉曲张 I 级组(n=28);左侧精索静脉曲张 II 级组(n=32);左侧精索静脉曲张 III 级组(n=32)。所有患者均接受精索蔓状静脉丛彩色双功能超声和阴囊闪烁显像检查。与健康对照组相比,精索静脉曲张患者的动脉血流速度、睾丸动脉直径和睾丸灌注明显下降,尤其是在中重度精索静脉曲张患者中更为显著。静脉平均直径与动脉直径、动脉血流速度、灌注指数、睾丸大小呈显著负相关,与灌注指数呈显著正相关。平均睾丸大小与动脉血流速度、灌注指数呈显著正相关,与动脉直径无显著相关性。结论:精索静脉曲张患者睾丸体积、睾丸灌注、血流速度和睾丸动脉直径明显下降。