Digestive Surgery and Endoscopy Unit, Bambino Gesù Hospital, 00165 Rome, Italy.
J Pediatr Surg. 2011 May;46(5):848-53. doi: 10.1016/j.jpedsurg.2011.02.014.
Esophageal stenting represents a new strategy to avoid multiple dilations owing to stenosis relapse. Our custom stent improves esophageal motility unlike the widespread self-expandable plastic esophageal stents. The aim of the study was to confirm the efficacy of treatment with silicone custom stents in esophageal stenosis (ES) in pediatric patients.
A silicone stent of 7-, 9-, or 12.7-mm external diameter is built coaxially on a nasogastric tube that guarantees the correct position. The 2 ends are tailored to allow food passage between stent and esophageal wall. All patients received dexamethasone (2 mg/kg per day) for 3 days and ranitidine/proton-pump inhibitors. Study approval was obtained from our ethical board.
From 1988 to 2010, 79 patients with ES, mean age 35.4 months (3-125 months), underwent esophageal hydrostatic/Savary dilations and custom-stent placement, left in place for at least 40 days. Stenting was effective in 70 (88.6%) of 79 patients. Fifty percent of the patients with effective treatment received only one dilation for stent placement. Fourteen patients received more stents successfully. There was one stent-related major complication.
Our custom stent improves treatment in ES. In caustic injuries, ES stenting represents the first option. In postsurgical ES, we stent after at least 5 dilations.
食管支架代表了一种避免因狭窄复发而多次扩张的新策略。我们的定制支架可改善食管运动功能,与广泛应用的自膨式塑料食管支架不同。本研究旨在证实硅酮定制支架治疗小儿食管狭窄(ES)的疗效。
在 7、9 或 12.7mm 外径的鼻胃管上同轴构建硅酮支架,以确保正确的位置。两端进行剪裁,以允许食物在支架和食管壁之间通过。所有患者均接受地塞米松(2mg/kg/天)3 天和雷尼替丁/质子泵抑制剂治疗。本研究获得了我们伦理委员会的批准。
1988 年至 2010 年,79 例 ES 患者(平均年龄 35.4 个月[3-125 个月])接受了食管水压/Savary 扩张和定制支架置入术,支架至少留置 40 天。79 例患者中,70 例(88.6%)治疗有效。50%的有效治疗患者仅接受一次扩张即可放置支架。14 例患者成功接受了更多的支架治疗。有 1 例支架相关的严重并发症。
我们的定制支架改善了 ES 的治疗效果。在腐蚀性损伤中,ES 支架治疗是首选。在手术后 ES 中,我们在至少 5 次扩张后进行支架置入。