School of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
Chem Commun (Camb). 2011 Jul 7;47(25):7063-4. doi: 10.1039/c1cc12456k. Epub 2011 May 27.
Mixture analysis by high resolution diffusion-ordered NMR spectroscopy (HR-DOSY) requires differences in both chemical shift and diffusion coefficient; resolution can be greatly enhanced by exploiting the chemical specificity of lanthanide shift reagent binding to increase chemical shift and diffusion dispersion simultaneously.
采用高分辨扩散排序核磁共振波谱（HR-DOSY）进行混合物分析，需要同时存在化学位移和扩散系数的差异；通过利用镧系元素位移试剂与靶分子的特异性结合来同时增加化学位移和扩散分散度，可以大大提高分辨率。
