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新型磷酸二酯酶抑制剂:与已上市药物的比较。

Newer phosphodiesterase inhibitors: comparison with established agents.

机构信息

Division of Urology, Department of Surgery, Duke University Medical Center, Box 2374, Durham, NC 27710, USA.

出版信息

Urol Clin North Am. 2011 May;38(2):155-63. doi: 10.1016/j.ucl.2011.03.005.

Abstract

Erectile dysfunction is defined as the consistent or recurrent inability to attain or maintain penile erection sufficient for sexual performance. Self-reported erectile dysfunction has increased significantly as men seek effective therapy, such as oral phosphodiesterase 5 inhibitors (PDE5i). PDE5i are now the drugs of choice in the initial therapy of erectile dysfunction. This review compares the currently available PDE5i with the second-generation PDE5i, which are soon to be available.

摘要

勃起功能障碍是指阴茎勃起持续或反复不能达到足够的勃起硬度以完成满意的性生活。由于男性寻求有效的治疗方法,如口服磷酸二酯酶 5 抑制剂(PDE5i),自我报告的勃起功能障碍显著增加。PDE5i 目前是勃起功能障碍初始治疗的首选药物。本文比较了目前可用的 PDE5i 与即将上市的第二代 PDE5i。

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