Department of Urology, Rush University Medical Center, 1725 West Harrison Street, Suite 352, Chicago, IL 60612, USA.
Urol Clin North Am. 2011 May;38(2):195-205. doi: 10.1016/j.ucl.2011.02.006.
The purpose of this article is to review the contemporary literature on nonsurgical therapies for Peyronie's disease (PD); focus on randomized, placebo-controlled trials; and review the latest guidelines for the management of PD from the International Consultation on Sexual Medicine. A combination of oral agents or intralesional injection with traction therapy may provide a synergy between the chemical effects of the drugs and the mechanical effects of traction. Until a reliable treatment emerges, some of the nonsurgical treatments discussed can be used to stabilize the scarring process and may result in some reduction of deformity with improved sexual function.
本文旨在回顾非手术治疗 Peyronie 病(PD)的当代文献;重点关注随机、安慰剂对照试验;并回顾国际性医学咨询最新的 PD 管理指南。口服药物或腔内注射联合牵引疗法可能在药物的化学作用和牵引的机械作用之间产生协同作用。在出现可靠的治疗方法之前,一些讨论过的非手术治疗方法可以用来稳定瘢痕形成过程,并可能导致一些畸形的改善和性功能的提高。