miRNAs 在细胞因子信号转导中的作用。
The role of miRNAs in cytokine signaling.
机构信息
Monash Institute of Medical Research, Monash University, Clayton, Victoria 3168, Australia.
出版信息
Front Biosci (Landmark Ed). 2011 Jun 1;16(6):2161-71. doi: 10.2741/3845.
DOI:10.2741/3845
PMID:21622168
Abstract
This review explores the relationship between cytokines and microRNAs (miRNAs). In particular, the regulation of miRNAs by pro-inflammatory cytokines, anti-inflammatory cytokines, interferons and transforming growth factor beta are examined, highlighting how miRNAs can mediate some of the known functions of these cytokines, as well as identifying novel gene targets, mechanisms and cross-talk between pathways.
摘要
这篇综述探讨了细胞因子和 microRNAs（miRNAs）之间的关系。特别是，检查了促炎细胞因子、抗炎细胞因子、干扰素和转化生长因子-β对 miRNAs 的调节，强调了 miRNAs 如何介导这些细胞因子的一些已知功能，并确定了新的基因靶标、机制和途径之间的交叉对话。
Zotero 插件