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贝尔面瘫——促肾上腺皮质激素(ACTH)治疗对预后不良患者的有益作用。

Bell's palsy-beneficial effect of treatment with adrenocorticotrophic hormone (ACTH) in patients with a poor prognosis.

作者信息

Ekstrand T, Glitterstam K

出版信息

Acta Otolaryngol. 1979 Jan-Feb;87(1-2):9-15. doi: 10.3109/00016487909126382.

DOI:10.3109/00016487909126382
PMID:216228
Abstract

In 111 patients with idiopathic peripheral facial paralysis (Bell's palsy) the prognosis was established during the first days of the disease, using sialometry and the stapedius reflex test in 102 patients. A poor prognosis was indicated in 36 patients. Treatment with adrenocorticotrophic hormone (ACTH) was commenced within 10 days (in the majority within 5 days) of the onset of the paresis in 31 of those patients with a poor prognosis. The recovery rate in the ACTH-treated group was superior compared with the untreated control group of patients with a poor prognosis. The difference is statistically significant. Those patients with a good prognosis were not treated but merely followed up. Some factors which could influence the result of the treatment are considered.

摘要

在111例特发性周围性面神经麻痹(贝尔麻痹)患者中,在疾病发作的头几天对102例患者采用唾液分泌测定法和镫骨肌反射试验确定预后。36例患者预后不良。其中31例预后不良的患者在麻痹发作后10天内(大多数在5天内)开始使用促肾上腺皮质激素(ACTH)治疗。ACTH治疗组的恢复率优于未治疗的预后不良对照组。差异具有统计学意义。预后良好的患者未接受治疗,仅进行随访。文中考虑了一些可能影响治疗结果的因素。

相似文献

1
Bell's palsy-beneficial effect of treatment with adrenocorticotrophic hormone (ACTH) in patients with a poor prognosis.贝尔面瘫——促肾上腺皮质激素(ACTH)治疗对预后不良患者的有益作用。
Acta Otolaryngol. 1979 Jan-Feb;87(1-2):9-15. doi: 10.3109/00016487909126382.
2
[Bell's palsy and stapedius reflex. 1. Prognosis based on the presence or absence of the reflex or its restoration].[贝尔麻痹与镫骨肌反射。1. 基于反射的有无或其恢复情况的预后]
Nihon Jibiinkoka Gakkai Kaiho. 1983 Feb 20;86(2):119-24.
3
[Significance of the examination of stapedial reflex evokability in the determination of prognosis in Bell's palsy of the facial nerve].[镫骨肌反射引出能力检查在面神经贝尔麻痹预后判定中的意义]
Cesk Otolaryngol. 1978 Dec;27(6):343-6.
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Speech discrimination in patients with Bell's palsy and a paralysed stapedius muscle.贝尔面瘫且镫骨肌麻痹患者的言语辨别能力
Clin Otolaryngol Allied Sci. 1995 Feb;20(1):59-62. doi: 10.1111/j.1365-2273.1995.tb00013.x.
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Surgical management of Bell's palsy.贝尔面瘫的外科治疗
Laryngoscope. 1999 Aug;109(8):1177-88. doi: 10.1097/00005537-199908000-00001.
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Bell's palsy--prognostic value of the stapedius reflex with contralateral stimulation.
J Laryngol Otol. 1979 Mar;93(3):271-5. doi: 10.1017/s0022215100087016.
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The prognostic value of the stapedius reflex in peripheral facial palsy.镫骨肌反射在外周性面神经麻痹中的预后价值。
Ear Nose Throat J. 1990 Oct;69(10):696-7.
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Prognosis in Bell's palsy based on symptoms, signs and laboratory data.基于症状、体征和实验室数据的贝尔麻痹预后
Acta Otolaryngol. 1982 May-Jun;93(5-6):407-14. doi: 10.3109/00016488209130898.
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Comparison of corticotrophin and prednisolone in treatment of idiopathic facial paralysis (Bell's palsy).促肾上腺皮质激素与泼尼松龙治疗特发性面神经麻痹(贝尔麻痹)的比较。
Br Med J. 1971 Oct 2;4(5778):20-2. doi: 10.1136/bmj.4.5778.20.
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Discriminant analysis in predicting prognosis of Bell's palsy.
Acta Otolaryngol. 1988 Sep-Oct;106(3-4):276-80. doi: 10.3109/00016488809106436.

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The clinical problem of Bell's palsy: is treatment with steroids effective?贝尔面瘫的临床问题:使用类固醇治疗是否有效?
Br J Gen Pract. 1996 Dec;46(413):743-7.