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Unsuccessful stem cell remobilization for autologous transplantation is predicted by renal impairment and a stem cell yield ≤ 0.5 X 10(6) CD34+ cells/kg at first mobilization.自体移植干细胞动员失败可由肾功能损害以及首次动员时干细胞产量≤0.5×10⁶ CD34⁺细胞/千克预测。
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Toxicity related to autologous peripheral blood haematopoietic progenitor cell infusion is associated with number of granulocytes in graft, gender and diagnosis of multiple myeloma.与自体外周血造血祖细胞输注相关的毒性与移植物中的粒细胞数量、性别以及多发性骨髓瘤的诊断有关。
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Incidence of Clostridium difficile-associated diarrhea before and after autologous peripheral blood stem cell transplantation for lymphoma and multiple myeloma.淋巴瘤和多发性骨髓瘤自体外周血干细胞移植前后艰难梭菌相关性腹泻的发生率
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Effectiveness and cost analysis of "just-in-time" salvage plerixafor administration in autologous transplant patients with poor stem cell mobilization kinetics.“即时”补救性普乐沙福给药在干细胞动员动力学不佳的自体移植患者中的有效性和成本分析。
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Stem cell mobilization in poor mobilizers with multiple myeloma or lymphoma before and after introduction of plerixafor: a single-center comparative analysis using a cost-efficient single fixed-dose schedule.普乐沙福引入前后多发性骨髓瘤或淋巴瘤低动员者的干细胞动员：使用经济高效的单一固定剂量方案的单中心比较分析
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Plerixafor plus granulocyte CSF can mobilize hematopoietic stem cells from multiple myeloma and lymphoma patients failing previous mobilization attempts: EU compassionate use data.培洛昔福联合粒细胞集落刺激因子可动员多发性骨髓瘤和淋巴瘤患者造血干细胞：欧盟同情用药数据。
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引用本文的文献

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Higher Age (≥60 Years) Increases the Risk for Adverse Events during Autologous Hematopoietic Stem Cell Transplantation.高龄（≥60岁）会增加自体造血干细胞移植期间发生不良事件的风险。
Cancers (Basel). 2023 Mar 3;15(5):1584. doi: 10.3390/cancers15051584.
2
The Role of Stem Cells in the Treatment of Cerebral Palsy: a Review.干细胞在脑瘫治疗中的作用：综述。
Mol Neurobiol. 2017 Sep;54(7):4963-4972. doi: 10.1007/s12035-016-0030-0. Epub 2016 Aug 13.
3
Adverse reactions during stem cell infusion in children treated with autologous and allogeneic stem cell transplantation.接受自体和异基因干细胞移植治疗的儿童在干细胞输注过程中的不良反应。
Bone Marrow Transplant. 2016 May;51(5):680-6. doi: 10.1038/bmt.2015.331. Epub 2016 Jan 11.

本文引用的文献

1
Occurrence and severity of adverse events after autologous hematopoietic progenitor cell infusion are related to the amount of granulocytes in the apheresis product.自体造血祖细胞输注后不良事件的发生及严重程度与单采产品中的粒细胞数量有关。
Transfusion. 2007 Jul;47(7):1268-75. doi: 10.1111/j.1537-2995.2007.01267.x.
2
Adverse events after infusions of cryopreserved hematopoietic stem cells depend on non-mononuclear cells in the infused suspension and patient age.
Cytotherapy. 2007;9(4):348-55. doi: 10.1080/14653240701326756.

The correlation between the granulocyte content in infused stem cells and side effects of the infusion.

作者信息

Richa Elie

出版信息

Blood Transfus. 2011 Jul;9(3):346. doi: 10.2450/2011.0103-10. Epub 2011 Apr 7.

DOI:10.2450/2011.0103-10
PMID:21627928
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3136606/
Abstract
摘要