Ikegawa Shiro
Laboratory for Bone and Joint Diseases, Center for Genomic Medicine, RIKEN, Japan.
Clin Calcium. 2011 Jun;21(6):826-30.
Osteoarthritis (OA) is a polygenic disease. Genetic factors are involved in its onset and progression. Identification of its genetic factor, i.e., the susceptibility genes for OA is rapidly in progress by using genomic approaches including genome-wide association study. Recent advance in the study of OA susceptibility genes is reviewed.
骨关节炎（OA）是一种多基因疾病。遗传因素参与其发病和进展。通过使用包括全基因组关联研究在内的基因组方法，对其遗传因素即OA易感基因的鉴定正在迅速推进。本文综述了OA易感基因研究的最新进展。
