Terpstra G K, Raaijmakers J A, Hamelink M, Kreukniet J
Ann Allergy. 1979 Jan;42(1):36-40.
To determine whether Haemophilus influenzae could be a factor in human atopy its effects were studied on the (para-)Sympathic Cyclic nucleotide-histamine axis in rats. Haemophilus influenzae vaccination induced changes in the cholinergic system compatible with higher cyclic GMP levels and enhanced histamine release. The authors suggest an involvement of the cholinergic system in Haemophilus influenzae vaccination effects.
为了确定流感嗜血杆菌是否可能是人类特应性的一个因素，研究了其对大鼠（副）交感神经环核苷酸 - 组胺轴的影响。流感嗜血杆菌疫苗接种引起了胆碱能系统的变化，这与较高的环鸟苷酸水平和组胺释放增加相一致。作者认为胆碱能系统参与了流感嗜血杆菌疫苗接种的效应。
