Noma Hidetaka, Funatsu Hideharu, Mimura Tatsuya, Shimada Katsunori
Department of Ophthalmology, Yachiyo Medical Center, Tokyo Women's Medical University, Owada-shinden, Chiba, Japan.
Clin Ophthalmol. 2011;5:679-85. doi: 10.2147/OPTH.S20527. Epub 2011 May 19.
Visual function and retinal morphology were investigated to elucidate the influence of ischemia in patients with branch retinal vein occlusion (BRVO) and macular edema. In 41 consecutive patients with BRVO aged 68.9 ± 10.0 years (22 women and 19 men), the area of capillary nonperfusion was measured by fluorescein angiography. Retinal thickness and retinal volume were measured by optical coherence tomography, and mean retinal sensitivity was calculated for each of 9 macular subfields. Mean visual acuity and macular sensitivity within the central subfield were not significantly correlated with the nonperfused area. However, the macular sensitivity within the central 5 subfields and all 9 subfields showed significant negative correlations with the nonperfused area. Also, macular thickness and volume within all 9 subfields were significantly correlated with the nonperfused area. In conclusion, evaluation of both the fovea and the entire macular region may be important in patients with ischemic BRVO.
为了阐明视网膜分支静脉阻塞（BRVO）和黄斑水肿患者局部缺血的影响，对其视觉功能和视网膜形态进行了研究。在41例连续的BRVO患者中，年龄为68.9±10.0岁（22例女性和19例男性），通过荧光素血管造影测量无灌注毛细血管区域。通过光学相干断层扫描测量视网膜厚度和视网膜体积，并计算9个黄斑亚区各自的平均视网膜敏感度。中心亚区内的平均视力和黄斑敏感度与无灌注区域无显著相关性。然而，中心5个亚区和所有9个亚区内的黄斑敏感度与无灌注区域呈显著负相关。此外，所有9个亚区内的黄斑厚度和体积与无灌注区域显著相关。总之，对于缺血性BRVO患者，评估中央凹和整个黄斑区域可能都很重要。
