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[实验性佝偻病大鼠的氧供应与组织代谢紊乱及其纠正]

[Disorders of oxygen supply and tissue metabolism and their correction in rats with experimental rickets].

作者信息

Shkiriak-Nizhnik Z A, Tarakhovskiĭ M L

出版信息

Fiziol Zh (1978). 1990 Mar-Apr;36(2):25-31.

PMID:2163334
Abstract

Indices of oxygen supply are studied in preadolescent rats with experimental rachitis. Disturbances in transport, capillary-tissue diffusion and oxygen utilization by tissues of the brain, liver and skeletal muscles correlating with a degree of the rachitis gravity are revealed. It is proved as possible to correct the revealed disturbances while using piracetam and vitamin D3. In this case manifestation of the tissue hypoxia in animals with experimental rachitis weakens and at the same time metabolic disturbances are eliminated.

摘要

对患有实验性佝偻病的青春期前大鼠的氧气供应指标进行了研究。发现大脑、肝脏和骨骼肌组织在运输、毛细血管-组织扩散和氧气利用方面的紊乱与佝偻病的严重程度相关。已证明使用吡拉西坦和维生素D3可以纠正所发现的紊乱。在这种情况下,患有实验性佝偻病的动物组织缺氧的表现会减弱,同时代谢紊乱也会消除。

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