Department of Respiratory Medicine, Sri Balaji Action Medical Institute, Delhi 110063, India.
Singapore Med J. 2011 May;52(5):e88-90.
Acute fibrinous and organising pneumonia (AFOP) is an unusual histopathological pattern of acute lung injury. The clinical manifestations, course and treatment of AFOP have yet to be characterised. All reported cases so far have described bilateral diffuse lung involvement radiologically. We report a case of an adolescent girl who presented with acute hypoxaemic respiratory failure with unilateral complete lung consolidation. She was initially diagnosed with severe community-acquired pneumonia. A computed tomography-guided percutaneous transthoracic trucut biopsy of the left lung revealed the classical histopathological pattern typically observed in AFOP. The patient responded well to treatment involving steroids. The uniqueness of such a presentation in AFOP prompted us to report this case.
急性纤维蛋白性和机化性肺炎（AFOP）是一种不常见的急性肺损伤的组织病理学模式。AFOP 的临床表现、病程和治疗尚待确定。到目前为止，所有报道的病例均描述了放射学上双侧弥漫性肺受累。我们报告了一例青少年女性，表现为急性低氧性呼吸衰竭伴单侧完全肺实变。她最初被诊断为严重社区获得性肺炎。经 CT 引导下经皮左肺穿刺活检显示出典型的 AFOP 组织病理学模式。患者对包括皮质类固醇在内的治疗反应良好。这种表现的独特性促使我们报告了这例病例。
