Look J O, Clay D J, Gong K, Messer H H
University of Minnesota, School of Dentistry, Minneapolis.
J Prosthet Dent. 1990 Jun;63(6):701-7. doi: 10.1016/0022-3913(90)90329-b.
The virucidal efficacy of germicides acting on an irreversible hydrocolloid surface is not known. Tests that are currently performed on germicides do not simulate the conditions under which the germicides are often used. One major concern for the dental profession is the disinfection of dental impressions, particularly irreversible hydrocolloid impressions. This study was designed to test the biocidal action of germicides against an enveloped virus on an irreversible hydrocolloid surface. The disinfection model, which was developed to simulate clinical conditions, specified the use of vesicular stomatitus virus, an animal virus amenable to safe handling. A 0.5% sodium hypochlorite spray inactivated the virus when the spray was allowed to remain on the impression 3 to 10 minutes. The iodophor disinfectant required a 3- to 10-minute immersion for total inactivation. Although 2% glutaraldehyde achieved total viral inactivation in less than 1 minute, the authors conclude that short disinfectant sprays, in general, are not an appropriate disinfection method.
作用于不可逆水胶体表面的杀菌剂的杀病毒效果尚不清楚。目前对杀菌剂进行的测试并未模拟杀菌剂常用的条件。牙科行业的一个主要关注点是牙科印模的消毒,尤其是不可逆水胶体印模。本研究旨在测试杀菌剂对不可逆水胶体表面包膜病毒的杀菌作用。为模拟临床条件而开发的消毒模型规定使用水疱性口炎病毒,这是一种易于安全处理的动物病毒。当0.5%次氯酸钠喷雾在印模上停留3至10分钟时可使病毒失活。碘伏消毒剂需要浸泡3至10分钟才能完全失活。尽管2%戊二醛在不到1分钟内实现了病毒的完全失活,但作者得出结论,一般来说,短时间的消毒剂喷雾不是一种合适的消毒方法。