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与表面消毒印模相比,浸渍银纳米颗粒的不可逆水胶体印模的抗菌效果——一项研究。

Antimicrobial Efficacy of Irreversible Hydrocolloid Impression Impregnated with Silver Nanoparticles Compared to Surface Disinfected Impressions - An Study.

作者信息

Rajendran Vaishnavi, Suma Karthigeyan, Ali Seyed Asharaf, Karthigeyan R, Kalarani G

机构信息

Department of Prosthodontics and Crown and Bridge, Rajah Muthiah Dental College and Hospital, Annamalai University, Chidambaram, Tamil Nadu, India.

Department of Oral and Maxillofacial Surgery, Sri Venkateshwaraa Dental College and Hospital, Puducherry, India.

出版信息

J Pharm Bioallied Sci. 2021 Jun;13(Suppl 1):S532-S536. doi: 10.4103/jpbs.JPBS_565_20. Epub 2021 Jun 5.

Abstract

BACKGROUND

Routine disinfection procedures have shown to cause incomplete disinfection and detrimental effects on dimensional properties of the impression. Hence, self-disinfecting impression materials impregnated with antimicrobial agents were developed.

PURPOSE

The purpose is to evaluate the antimicrobial efficacy of silver nanoparticles (AgNPs) impregnated in irreversible hydrocolloid (IH) impression material in conditions.

MATERIALS AND METHODS

This study comprised of four groups-IH impressions disinfected by immersion in 2% glutaraldehyde, IH impregnated with AgNPs of sizes 80-100 nm and 20-30 nm, nondisinfected impressions as control. Five impressions were made for each group and a total of 20 impression samples were made. The antimicrobial action of each sample was assessed by counting the number of colony forming units and by disc diffusion method.

RESULTS

The results were obtained and the data were statistically analyzed by Kruskal-Wallis test and tabulated. The results revealed that AgNPs of size 80-100 nm when impregnated in irreversible impression material showed effective antimicrobial action.

CONCLUSION

The anti-microbial action of 80-100 nm AgNP impregnated IH impressions is comparable to that of impressions disinfected by immersion in 2% glutaraldehyde for 10 min.

摘要

背景

常规消毒程序已被证明会导致消毒不彻底,并对印模的尺寸特性产生不利影响。因此,开发了浸渍有抗菌剂的自消毒印模材料。

目的

目的是评估浸渍在不可逆水胶体(IH)印模材料中的银纳米颗粒(AgNPs)在特定条件下的抗菌效果。

材料与方法

本研究包括四组——通过浸入2%戊二醛进行消毒的IH印模、浸渍有尺寸为80 - 100纳米和20 - 30纳米的AgNPs的IH印模、未消毒的印模作为对照。每组制作五个印模,共制作20个印模样本。通过计算菌落形成单位数量和纸片扩散法评估每个样本的抗菌作用。

结果

获得结果并通过Kruskal - Wallis检验对数据进行统计分析并制成表格。结果显示,当尺寸为80 - 100纳米的AgNPs浸渍在不可逆印模材料中时,显示出有效的抗菌作用。

结论

浸渍有80 - 100纳米AgNP的IH印模的抗菌作用与浸入2%戊二醛中10分钟消毒的印模相当。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f0b/8375848/5500379485c0/JPBS-13-532-g001.jpg

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