Nakamura M, Watanabe K, Kobayashi T, Negoro T, Aso K, Furune S, Takahashi I, Yamamoto N
Department of Pediatrics, Nagoya University School of Medicine.
No To Hattatsu. 1990 May;22(3):284-9.
We report an 11-year-old boy with left pyramidal signs followed by progressive dystonia, mental deterioration, bradykinesia and bradyarthria. Evaluation included a CT scan which showed bilateral lesions in the basal ganglia, and an elevated serum B-HCG. Those findings suggested a germ cell tumor. The patient was treated with radiation therapy with improvement in neurologic deficits, decreased size of the lesions on CT and a decline in serum B-HCG. The clinical response to radiation treatment is compatible with a germ cell tumor.
我们报告了一名11岁男孩,其出现左侧锥体束征,随后出现进行性肌张力障碍、智力减退、运动迟缓及构音障碍。评估包括CT扫描,结果显示基底神经节双侧病变,血清β-人绒毛膜促性腺激素(B-HCG)升高。这些发现提示为生殖细胞肿瘤。该患者接受了放射治疗,神经功能缺损得到改善,CT上病变大小减小,血清B-HCG下降。对放射治疗的临床反应符合生殖细胞肿瘤。