Guo Z
Zhonghua Yi Xue Za Zhi. 1990 Mar;70(3):130-2, 10.
Plasma atrial natriuretic peptide (ANP) Levels were measured by radioimmunoassay both in 38 infants with pneumonia and 20 infants with pneumonia associated with congestive heart failure (CHF). 10 of the 20 infants with CHF were examined with echocardiography during CHF and recovery period. The plasma ANP Levels in the pneumonia group was 424.3 +/- 214.4 pg/ml (mean +/- SD). Which was significantly higher than that of the control group (P less than 0.01). The plasma ANP levels in pneumonia with CHF group was 684.4 +/- 366.9 pg/ml, which was significantly higher than that in the group of pneumonia without CHF (P less than 0.01). Positive linear correlation was found between the mean pulmonary artery pressure and plasma ANP content (r = 0.717, P less than 0.05). The results of this study suggest that plasma ANP concentration may give useful information on the indication of using vasodilators in infant with pneumonia. It may also be taken as a practical diagnostic indicator in pneumonia associated with CHF.
采用放射免疫分析法测定了38例肺炎患儿和20例合并充血性心力衰竭（CHF）的肺炎患儿的血浆心房利钠肽（ANP）水平。对20例CHF患儿中的10例在CHF期和恢复期进行了超声心动图检查。肺炎组血浆ANP水平为424.3±214.4 pg/ml（均值±标准差），显著高于对照组（P＜0.01）。合并CHF的肺炎组血浆ANP水平为684.4±366.9 pg/ml，显著高于无CHF的肺炎组（P＜0.01）。平均肺动脉压与血浆ANP含量呈正线性相关（r = 0.717，P＜）。本研究结果提示，血浆ANP浓度可能为肺炎患儿使用血管扩张剂的指征提供有用信息。它也可作为合并CHF的肺炎的实用诊断指标。 0.05
