Laboratório de Genômica e Expressão, Departamento de Genética e Evolução, Instituto de Biologia, Universidade Estadual de Campinas, Campinas, SP Brazil.
Genet Mol Biol. 2009 Jul;32(3):634-9. doi: 10.1590/S1415-47572009000300030. Epub 2009 Sep 1.
The web application D-Maps provides a user-friendly interface to researchers performing studies based on microarrays. The program was developed to manage and process one- or two-color microarray data obtained from several platforms (currently, GeneTAC, ScanArray, CodeLink, NimbleGen and Affymetrix). Despite the availability of many algorithms and many software programs designed to perform microarray analysis on the internet, these usually require sophisticated knowledge of mathematics, statistics and computation. D-maps was developed to overcome the requirement of high performance computers or programming experience. D-Maps performs raw data processing, normalization and statistical analysis, allowing access to the analyzed data in text or graphical format. An original feature presented by D-Maps is GEO (Gene Expression Omnibus) submission format service. The D-MaPs application was already used for analysis of oligonucleotide microarrays and PCR-spotted arrays (one- and two-color, laser and light scanner). In conclusion, D-Maps is a valuable tool for microarray research community, especially in the case of groups without a bioinformatic core.
D-Maps 网络应用程序为从事基于微阵列研究的研究人员提供了一个用户友好的界面。该程序旨在管理和处理来自多个平台（目前为 GeneTAC、ScanArray、CodeLink、NimbleGen 和 Affymetrix）的一种或两种颜色的微阵列数据。尽管有许多算法和许多旨在在互联网上进行微阵列分析的软件程序，但这些程序通常需要对数学、统计学和计算有深入的了解。D-Maps 的开发是为了克服对高性能计算机或编程经验的要求。D-Maps 执行原始数据处理、标准化和统计分析，允许以文本或图形格式访问分析后的数据。D-Maps 提供的一个独特功能是 GEO（基因表达综合数据库）提交格式服务。该 D-Maps 应用程序已用于寡核苷酸微阵列和 PCR 斑点阵列（一种和两种颜色、激光和光扫描仪）的分析。总之，D-Maps 是微阵列研究社区的一个有价值的工具，特别是对于没有生物信息核心的群体。
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