环磷酸腺苷（cAMP）诱导的螺旋神经元突触反应增强。
Cyclic adenosine monophosphate (cAMP)-induced potentiation of synaptic responses in Helix neurons.
作者信息
Borisova O V
机构信息
Brain Research Institute, All-Union Center of Mental Health, USSR Medical Academy, Moscow.
出版信息
Cell Mol Neurobiol. 1990 Jun;10(2):275-9. doi: 10.1007/BF00734580.
Abstract
- The effect of intracellularly injected cAMP on the amplitude of excitatory postsynaptic potentials was studied using identified neurons of the snail Helix pomatia. 2. In 25% of the experiments, postsynaptic cAMP elevation caused a pronounced augmentation of the excitatory postsynaptic potential (EPSP) amplitude, lasting up to 15-30 min. 3. The results suggest that a cAMP increase in the postsynaptic neuron may be involved in the enhancement of synaptic efficiency.
摘要
- 利用鉴定出的苹果螺神经元，研究了细胞内注射环磷酸腺苷（cAMP）对兴奋性突触后电位幅度的影响。2. 在25%的实验中，突触后环磷酸腺苷水平升高导致兴奋性突触后电位（EPSP）幅度显著增大，持续15 - 30分钟。3. 结果表明，突触后神经元中环磷酸腺苷的增加可能参与了突触效率的增强。
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本文引用的文献
1
The effect of intracellular cAMP injections on stationary membrane conductance and voltage- and time-dependent ionic currents in identified snail neurons.细胞内注射环磷酸腺苷（cAMP）对特定蜗牛神经元的静息膜电导以及电压和时间依赖性离子电流的影响。
Brain Res. 1983 Jun 6;268(2):321-38. doi: 10.1016/0006-8993(83)90499-7.
2
cAMP-mediated decrease in K+ conductance evoked by serotonin and dopamine in the same neuron: a biochemical and physiological single-cell study.环磷酸腺苷介导的血清素和多巴胺在同一神经元中诱发的钾离子电导降低：一项生化和生理单细胞研究。
Proc Natl Acad Sci U S A. 1982 Dec;79(24):7934-8. doi: 10.1073/pnas.79.24.7934.
3
Molecular biology of learning: modulation of transmitter release.学习的分子生物学：神经递质释放的调节
Science. 1982 Oct 29;218(4571):433-43. doi: 10.1126/science.6289442.
4
Serotonin and cyclic AMP close single K+ channels in Aplysia sensory neurones.血清素和环磷酸腺苷可关闭海兔感觉神经元中的单个钾离子通道。
Nature. 1982 Sep 30;299(5882):413-7. doi: 10.1038/299413a0.
5
Serotonin-induced hyperpolarization of an indentified Aplysia neuron is mediated by cyclic AMP.
Proc Natl Acad Sci U S A. 1980 Aug;77(8):5013-7. doi: 10.1073/pnas.77.8.5013.
6
A novel membrane sodium current induced by injection of cyclic nucleotides into gastropod neurones.通过向腹足纲神经元注射环核苷酸诱导产生的一种新型膜钠电流。
J Physiol. 1984 Sep;354:139-62. doi: 10.1113/jphysiol.1984.sp015368.
7
Stimulation of a sodium influx by cAMP in Helix neurons.环磷酸腺苷（cAMP）对螺旋神经元中钠内流的刺激作用。
Brain Res. 1983 Oct 16;276(2):289-96. doi: 10.1016/0006-8993(83)90736-9.
8
Physiological and pharmacological identification of neurons in the central nervous system of Helix pomatia L.苹果螺（Helix pomatia L.）中枢神经系统中神经元的生理和药理学鉴定
Acta Physiol Acad Sci Hung. 1969;35(1):19-30.
9
Chemical transmission in invertebrate central nervous systems and neuromuscular junctions.无脊椎动物中枢神经系统和神经肌肉接头中的化学传递。
Physiol Rev. 1973 Jan;53(1):1-119. doi: 10.1152/physrev.1973.53.1.1.
10
Cellular analysis of associative learning.联想学习的细胞分析
Physiol Rev. 1987 Apr;67(2):329-439. doi: 10.1152/physrev.1987.67.2.329.
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