Cilleruelo Ramos Angel, Martínez Barenys Carlos, Paradela de la Morena Marina, Varela Gonzalo
Servicio de Cirugía Torácica, Hospital Universitario de Valladolid, Valladolid, España.
Arch Bronconeumol. 2011;47 Suppl 3:2-4. doi: 10.1016/S0300-2896(11)70021-7.
The present article discusses the two most up-to-date clinical practice guidelines containing the recommendations of US and European scientific societies on preoperative assessment of the risk of lung resection. Despite some differences between the two documents, both guidelines agree on the importance of routine preoperative measurement of diffusion lung capacity for carbon monoxide (DLCO) in the predictive value of exercise tests, especially measurement of maximal oxygen uptake per minute (VO(2max)). Precisely because of its ability to predict the risk of operative death, VO(2max) should be measured in patients with a forced expiratory volume in 1 second (FEV1) or DLCO below 80% of the theoretical value. The authors recommend using one of the two above-mentioned guidelines in clinical practice and periodically auditing the results to compare them with in-hospital mortality for lung resection in Europe, currently available through the European Association of Thoracic Surgeons. There is currently no validated risk index that could be directly applied in clinical decision making in lung resection.
本文讨论了两份最新的临床实践指南,其中包含美国和欧洲科学协会关于肺切除术前风险评估的建议。尽管这两份文件存在一些差异,但两个指南都认同术前常规测量一氧化碳弥散肺容量(DLCO)对于运动试验预测价值的重要性,尤其是每分钟最大摄氧量(VO₂max)的测量。正是由于其能够预测手术死亡风险,对于1秒用力呼气量(FEV₁)或DLCO低于理论值80%的患者,应测量VO₂max。作者建议在临床实践中使用上述两份指南中的一份,并定期审核结果,以便与目前通过欧洲胸外科医师协会可获取的欧洲肺切除院内死亡率进行比较。目前尚无经过验证的风险指数可直接应用于肺切除的临床决策。