子宫内膜中 Hedgehog 表达减少与子宫内膜异位症相关。
Endometrial Indian hedgehog expression is decreased in women with endometriosis.
机构信息
Program on Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892-1109, USA.
出版信息
Fertil Steril. 2011 Jun 30;95(8):2738-41.e1-3. doi: 10.1016/j.fertnstert.2011.05.018. Epub 2011 Jun 2.
Abstract
Nuclear and cytoplasmic endometrial expression of Indian hedgehog increased from the late proliferative to mid and late secretory phases in 26 healthy volunteers compared with 30 women with endometriosis. The abnormal expression of Indian hedgehog protein in women with endometriosis suggests a resistance to P action.
摘要
与 30 名子宫内膜异位症患者相比，26 名健康志愿者的子宫内膜核和细胞质中印度刺猬因子的表达从增殖晚期增加到中晚期分泌期。子宫内膜异位症患者印度刺猬因子蛋白的异常表达表明对孕激素作用的抵抗。
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本文引用的文献
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Progesterone resistance in a baboon model of endometriosis.子宫内膜异位症狒狒模型中的孕激素抵抗。
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